Current RMA Instruments
| Reasonable Hypothesis SOP | 80 of 2020 |
| Balance of Probabilities SOP | 81 of 2020 |
Changes from previous Instruments
ICD Coding
- ICD-9-CM Codes: 180, 233.1, 622.1
- ICD-10-AM Codes: C53, D06, N87.2
Brief description
This is a primary cancer of the uterine cervix (the neck of the uterus/womb). The RMA SOP also covers advanced precancerous lesions, known as cervical intraepithelial neoplasia (CIN) grade III (also referred to as carcinoma-in-situ and severe cervical dysplasia).
Confirming the diagnosis
This diagnosis is based on histological evaluation of a cervical biopsy.
The relevant medical specialist is a gynaecologist or gynaecological oncologist.
Additional diagnoses covered by SOP
- Adenocarcinoma of the cervix
- Adenosquamous carcinoma of the cervix
- Carcinoma in situ of the cervix
- Cervical intraepithelial neoplasia grade 3 (CIN III)
- Severe cervical dysplasia
- Squamous cell carcinoma of the cervix
Conditions excluded from SOP
- Adenosarcoma of the cervix#
- Carcinosarcoma of the cervix#
- Cervical intraepithelial neoplasm grade 1 (CIN I)#
- Cervical intraepithelial neoplasm grade 2 (CIN II)#
- Malignant melanoma of the cervix#
- Mild cervical dysplasia#
- Moderate cervical dysplasia#
- Squamous intraepithelial lesion#
- Melanoma in situ of the cervix#
- Soft tissue sarcoma of the cervix*
- Non-Hodgkin lymphoma of the cervix*
- Hodgkin’s lymphoma of the cervix*
* another SOP applies
# non-SOP condition
Clinical onset
The condition is usually asymptomatic and is detected by cervical screening or otherwise on pelvic examination. Symptomatic presentations may include vaginal bleeding or discharge.
Clinical worsening
The only SOP worsening factor is for inability to obtain appropriate clinical management. The appropriate treatment varies with the stage and extent of disease. The course of the condition is highly variable, with early stage disease having a favourable prognosis.