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Statements of Principles

Cerebral ischaemia - Treatment with tamoxifen Factor

Definition

Tamoxifen is a non-steroidal anti-oestrogen drug which is used in the prevention or treatment of malignant neoplasms such as breast cancer and metastatic melanoma, or to stimulate ovulation in infertility.

Establishing a history of treatment with Tamoxifen

A history of ingestion of Tamoxifen should be documented in the evidence.  Genox, Nolvadex and Tamosin are also brand name  medications that contain this drug.

If doctors' notes and hospitals' records have been destroyed or can no longer be obtained, a statement that Tamoxifen was taken at a particular time will generally be accepted, unless there is contradictory evidence.  Seek medical advice if it is unclear whether the claimed treatment with Tamoxifen is medically feasible.

Last reviewed for CCPS 24 May 2007.

Preliminary questions [37213]

16833 there is some evidence that treatment with tamoxifen may be a factor in the development of the condition under consideration.

14054 the veteran has been treated with tamoxifen at some time.

14056 the treatment with tamoxifen was given for an illness or injury which is identifiable.

37212 for the identified illness or injury, the veteran was treated with tamoxifen for a continuous period of at least the 21 days before the clinical onset of the condition under consideration, a cerebrovascular accident.

37214  the veteran has established the causal connection between the identified illness or injury for which the treatment with tamoxifen was given and VEA service for the clinical onset of cerebrovascular accident.

37215   the veteran has established the causal connection between the identified illness or injury for which the treatment with tamoxifen was given and operational service for the clinical onset of cerebrovascular accident.

or

37216   the veteran has established the causal connection between the identified illness or injury for which the treatment with tamoxifen was given and eligible service for the clinical onset of cerebrovascular accident.

Clinical onset and operational service [37215]

14060  the identified illness or injury for which the treatment with tamoxifen was given is causally related to operational service.

Clinical onset and eligible service [37216]

14061  the identified illness or injury for which the treatment with tamoxifen was given is causally related to eligible service.