8.Generally, there is consensus between experts within the Centres for Disease Control (Atlanta) that the following criteria currently best represent a diagnosis for CFS (Holmes et al 1988 Chronic Fatigue Syndrome: A Working Case Definition. Annals of Internal Medicine. 108:387-89):
9.For diagnosis, both the folllowing major criteria must be present:
Major criteria
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New onset fatigue lasting longer than 6 months with a 50% reduction in activity.
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No other medical or psychiatric conditions that could cause symptoms.
10.Additionally, at least 6 of the following minor symptoms must be present where physical signs are also apparent, or 8 minor symptoms where no physical signs are apparent:
Minor criteria - symptoms
SYMPTOMS which must begin at or after the onset of fatigue
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Low grade fever (ie 37.5 — û — C to 38.6 — û — C);
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Sore throat;
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Painful cervical or axillary (armpit) lymph node enlargement or disease;
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Generalised muscle weakness;
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Myalgias (muscle pains);
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Fatigue lasting 24 hours or more after moderate exercise;
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Headaches;
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Migratory arthralgia (joint pain);
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Sleep disturbance (hypersomnia or insomnia);
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Neuropsychological complaints (one or more of photophobia, absent/depressed vision, such as visual scotomas, forgetfulness, irritability, confusion, difficulty concentrating, depression);
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Acute onset (over a few hours to a few days).
11.Where only 6 of the above symptoms are diagnosed, at least 2 of the following physical signs must be present:
Minor criteria - physical signs (which must be documented by a medical practitioner twice, at least 1 month apart)
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Low grade fever;
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Pharynx inflammation, or pharyngitis;
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Cervical or axillary (armpit) lymph node enlargement or disease.