Reasonable Hypothesis SOP [1] | 60 of 2020 |
Balance of Probabilities SOP [2] | 61 of 2020 |
SOP Bulletin 216 [3]
Pure red cell aplasia is a rare cause of severe anaemia. It is characterised by a very low red cell count and absence or near absence of red cell precursors in the bone marrow, with normal white cell and platelet production.
Diagnosis requires a bone marrow examination and a full blood count, with other investigations also likely to be performed to investigate potential causes.
The relevant medical specialist is a haematologist.
* another SOP applies
# non-SOP condition
The condition tends to occur in older subjects and had an insidious onset. Clinical onset will be based on the laboratory findings. Once the diagnosis has been confirmed, the clinical picture may allow backdating of onset to a earlier time.
The only worsening factors are for inability to obtain appropriate clinical management and for being pregnant. The condition may resolve in some people and persist in others, depending on the underlying cause. Treatment may include immunosupression and transfusions. Long term survival is usual with appropriate therapy.
Links
[1] http://www.rma.gov.au/assets/SOP/2020/a3d6c9bbaf/060.pdf
[2] http://www.rma.gov.au/assets/SOP/2020/67c9a1647f/061.pdf
[3] https://clik.dva.gov.au/system/files/media/SOP%20Bulletin%20216.pdf