Reasonable Hypothesis SOP [1] | 33 of 2021 |
Balance of Probabilities SOP [2] | 34 of 2021 |
SOP Bulletin 219 [3]
This is a cancer of immature white blood cells (lymphoblasts). There are two overlapping clinical presentations of the same disease - leukaemia, when bone marrow blast cells predominate, and lymphoma, when a mass lesion in the mediastinum or elsewhere is the predominant feature.
Diagnosis is usually suspected based on a finding of swollen lymph nodes or a blood test showing abnormal white cells. A bone marrow biopsy is required to confirm the diagnosis and differentiate the condition from other diseases.
The relevant medical specialist is a haematologist.
* another SOP applies
# non-SOP condition
Clinical onset will be when the diagnosis was confirmed, or shortly before that time if characteristic symptoms were present, such as easy bruising/bleeding, recurrent infections or symptoms from anaemia. 75% of cases occur in children under 6, but there is a second peak in adults > 60 years old.
The only worsening factor is for inability to obtain appropriate clinical management. The prognosis in adults is generally poor. Worsening beyond the normal progression of the disease will be difficult to establish and will require specialist opinion.
Place holder node for Rulebase for acute lymphoid leukaemia
Acute lymphoid leukaemia - A course of therapeutic radiation Factor
Last reviewed for CCPS 21 June 2002.
Preliminary questions [32015]
7629 [5] there is some evidence that therapeutic radiation may be a factor in the development of the condition under consideration.
5031 [5] the veteran has received a course of therapeutic radiation at some time.
32021 [6] the veteran underwent a course of therapeutic radiation for the treatment of an illness or injury which is identifiable. 32017 — the veteran has established the causal connection between the course of therapeutic radiation and VEA service for the clinical onset of acute lymphoid leukaemia. 32019 — the veteran has established the causal connection between the course of therapeutic radiation and eligible service for the clinical onset of acute lymphoid leukaemia. or 32018 — the veteran has established the causal connection between the course of therapeutic radiation and operational service for the clinical onset of acute lymphoid leukaemia. Clinical onset and operational service [32018] 5326 — the identified illness or injury for which the course of therapeutic radiation was received is causally related to operational service. [8] [9] Clinical onset and eligible service [32019]
5327 — the identified illness or injury for which the course of therapeutic radiation was received is causally related to eligible service. [12] [9]
Acute lymphoid leukaemia - Atomic radiation Factor
Last reviewed for CCPS 21 June 2002.
Investigative Documents
Claimant Report - Exposure to Atomic Radiation [CR9171] Preliminary questions [1659]
1790 — the veteran has established the causal connection between atomic radiation and VEA service for the clinical onset of acute lymphoid leukaemia.
31993 — the veteran has established the causal connection between atomic radiation and operational service for the clinical onset of acute lymphoid leukaemia.
or
31994 — the veteran has established the causal connection between atomic radiation and eligible service for the clinical onset of acute lymphoid leukaemia.
Clinical onset and operational service [31993]
31995 [14] the veteran received a cumulative equivalent dose of at least 0.01 Sievert of atomic radiation to the bone marrow. the veteran received a cumulative equivalent dose of at least 0.01 Sievert of atomic radiation to the bone marrow where this dose was accumulated at least two years before the clinical onset of the condition under consideration. the veteran's operational service made a material contribution to the cumulative equivalent dose of at least 0.01 Sievert of atomic radiation to the bone marrow where this dose was accumulated at least two years before the clinical onset of the condition under consideration. the cumulative equivalent dose of at least 0.01 Sievert of atomic radiation to the bone marrow, to which operational service made a material contribution and this dose was accumulated at least two years before the clinical onset of the condition under consideration, was due to the veteran's serious default, wilful act or serious breach of discipline. Clinical onset and eligible service [31994]
Acute lymphoid leukaemia - HTLV-1 infection Factor
Last reviewed for CCPS 21 June 2002.
Preliminary questions [1665]
10932 [22] there is some evidence that being infected with HTLV-1 may be a factor in the development of acute lymphoid leukaemia.
32023 [23] the veteran has Adult T-cell lymphoma-leukaemia. the veteran has been infected with HTLV-1.
1668 [25] the veteran was infected with HTLV-1 before the clinical onset of acute lymphoid leukaemia. [26]
1669 — the veteran has established the causal connection between being infected with HTLV-1 and VEA service for the clinical onset of acute lymphoid leukaemia.
1671 — the veteran has established the causal connection between being infected with HTLV-1 and operational service for the clinical onset of acute lymphoid leukaemia.
or
10933 — the veteran has established the causal connection between being infected with HTLV-1 and eligible service for the clinical onset of acute lymphoid leukaemia.
Clinical onset and operational service [1671]
1672 — being infected with HTLV-1 is causally related to operational service. [27] [28]
Clinical onset and eligible service [10933]
8081 — being infected with HTLV-1 is causally related to eligible service. [29] [28]
Acute lymphoid leukaemia - Inability to obtain appropriate clinical management for acute lymphoid leukaemia Factor
Last reviewed for CCPS 21 June 2002.
Investigative Documents
Medical Report - Inability to Obtain Appropriate Clinical Management - [GQACM] Preliminary questions [10912] 11109 — the condition under consideration has been accepted on the basis of inability to obtain appropriate clinical management for the condition under consideration.
7334 [31] the clinical onset of the condition under consideration occurred after the end of the veteran's last period of VEA service. the condition under consideration permanently worsened. the veteran was unable to obtain appropriate clinical management for the condition under consideration at some time.
7379 [34] the inability to obtain appropriate clinical management for the condition under consideration contributed to the clinical worsening of the condition under consideration. 11234 — the veteran has established the causal connection between the inability to obtain appropriate clinical management for the condition under consideration and VEA service for the clinical worsening of the condition under consideration. 11235 — the veteran has established the causal connection between the inability to obtain appropriate clinical management for the condition under consideration and operational service for the clinical worsening of the condition under consideration. or 11236 — the veteran has established the causal connection between the inability to obtain appropriate clinical management for the condition under consideration and eligible service for the clinical worsening of the condition under consideration. Clinical worsening and operational service [11235] or 7390 — the identified illness or injury which prevented the veteran from obtaining appropriate clinical management for the condition under consideration is causally related to operational service. [38] [39] Clinical worsening and eligible service [11236] or 7391 — the identified illness or injury which prevented the veteran from obtaining appropriate clinical management for the condition under consideration is causally related to eligible service. [38] [39]
Acute lymphoid leukaemia - Infection with the Epstein-Barr virus Factor
Last reviewed for CCPS 21 June 2002.
Preliminary questions [10911]
32012 [46] there is some evidence that being infected with Epstein-Barr virus may be a factor in the development of the condition under consideration.
10920 [47] the veteran has ALL L3 subtype. the veteran has been infected with Epstein-Barr virus at some time. the veteran became infected with Epstein-Barr virus at least one year before the clinical onset of acute lymphoid leukaemia. [50]
10922 — the veteran has established the causal connection between being infected with Epstein-Barr virus and VEA service for the clinical onset of acute lymphoid leukaemia.
10924 — the veteran has established the causal connection between being infected with Epstein-Barr virus and operational service for the clinical onset of acute lymphoid leukaemia.
or
10925 — the veteran has established the causal connection between being infected with Epstein-Barr virus and eligible service for the clinical onset of acute lymphoid leukaemia.
Clinical onset and operational service [10924]
32013 — being infected with Epstein-Barr virus is causally related to operational service. [51] [52]
Clinical onset and eligible service [10925]
32014 — being infected with Epstein-Barr virus is causally related to eligible service. [53] [52]
Links
[1] http://www.rma.gov.au/assets/SOP/2021/eae501d9e8/033.pdf
[2] http://www.rma.gov.au/assets/SOP/2021/705c092af2/034.pdf
[3] https://clik.dva.gov.au/system/files/media/SOP%20Bulletin%20219.pdf
[4] https://clik.dva.gov.au/user/login?destination=comment/reply/63192%23comment-form
[5] https://clik.dva.gov.au/ccpsb029rc-15
[6] clikpopup://CCPS/A course of therapeutic radiation for treatment of ill or inj
[7] clikpopup://CCPS/reject32021No
[8] clikpopup://CCPS/reject32020No
[9] clikpopup://CCPS/reject5326,5327No
[10] clikpopup://CCPS/Course of therapeutic radiation for treatment of ill or inj was 2 years before onset
[11] clikpopup://CCPS/reject32022No
[12] clikpopup://CCPS/reject5327No
[13] https://clik.dva.gov.au/ccpsclaimant-240
[14] https://clik.dva.gov.au/1659-atomic-radiation
[15] clikpopup://CCPS/reject31995No
[16] clikpopup://CCPS/reject31996No
[17] clikpopup://CCPS/reject35162No
[18] clikpopup://CCPS/rejectwilful
[19] clikpopup://CCPS/reject32001No
[20] clikpopup://CCPS/reject32003No
[21] clikpopup://CCPS/reject32002No
[22] clikpopup://CCPS/HTLV-1 infection
[23] https://clik.dva.gov.au/standard-commentary-128
[24] clikpopup://CCPS/reject32023No
[25] clikpopup://CCPS/HTLV-1 infection before onset of acute lymphoid leukaemia
[26] clikpopup://CCPS/reject1668No
[27] clikpopup://CCPS/reject1672No
[28] clikpopup://CCPS/reject1672,8081No
[29] clikpopup://CCPS/reject8081No
[30] https://clik.dva.gov.au/ccpsother-31
[31] https://clik.dva.gov.au/node/71091
[32] clikpopup://CCPS/Reject/OnsetAfterService
[33] clikpopup://CCPS/Reject/NoPermanentWorsening
[34] clikpopup://CCPS/Acute lymphoid leukaemia/ACM %C2%96 contributed to worsening
[35] clikpopup://CCPS/ACM/NoContribution
[36] clikpopup://CCPS/ACM/NotOpService
[37] clikpopup://CCPS/ACM/NotOperDuties
[38] clikpopup://CCPS/ACM/NoIllness
[39] clikpopup://CCPS/reject7390,7391No
[40] clikpopup://CCPS/Acute lymphoid leukaemia/ACM %C2%96 onset prior to operational service
[41] clikpopup://CCPS/ACM/OnsetFailOper
[42] clikpopup://CCPS/ACM/NotEligService
[43] clikpopup://CCPS/ACM/NotEligDuties
[44] clikpopup://CCPS/Acute lymphoid leukaemia/ACM %C2%96 onset prior to eligible service
[45] clikpopup://CCPS/ACM/OnsetFailElig
[46] https://clik.dva.gov.au/ccpsb006rc-2
[47] clikpopup://CCPS/Acute lymphoid leukaemia L3 subtype
[48] clikpopup://CCPS/reject10920No
[49] clikpopup://CCPS/reject10921No
[50] clikpopup://CCPS/reject10926No
[51] clikpopup://CCPS/reject32013No
[52] clikpopup://CCPS/reject32013,32014No
[53] clikpopup://CCPS/reject32014No