A haematological or lymphoproliferative disorder

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/haematological-or-lymphoproliferative-disorder

A nutritional deficiency

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/nutritional-deficiency

A systemic disease for peripheral neuropathy

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/systemic-disease-peripheral-neuropathy

A systemic vasculitis

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/systemic-vasculitis

A viral or bacterial or protozoal infection

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/viral-or-bacterial-or-protozoal-infection

Acute cholinergic poisoning

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/acute-cholinergic-poisoning

Alcohol consumption

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/alcohol-consumption

Alcohol dependence or alcohol abuse

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/alcohol-dependence-or-alcohol-abuse

An inflammatory connective tissue disease

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/inflammatory-connective-tissue-disease

Critical illness requiring mechanical ventilation support

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/critical-illness-requiring-mechanical-ventilation-support

Diabetes mellitus

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/diabetes-mellitus

Electrical or thermal burn

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/electrical-or-thermal-burn

Exposure to a specified chemical

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/exposure-specified-chemical

Exposure to a volatile substance

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/exposure-volatile-substance

Exposure to TCDD

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/exposure-tcdd

Hypothyroidism

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/hypothyroidism

Inability to obtain appropriate clinical management for peripheral neuropathy

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/inability-obtain-appropriate-clinical-management-peripheral-neuropathy

Inhalant abuse or inhalant dependence

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/inhalant-abuse-or-inhalant-dependence

Malignant neoplasm

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/malignant-neoplasm

Poisoning with an organic toxin or a specified metal

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/poisoning-organic-toxin-or-specified-metal

Treatment with a drug from list 1

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/treatment-drug-list-1

Treatment with a drug from list 2

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/treatment-drug-list-2

Treatment with cisplatin

Current RMA Instruments

Reasonable Hypothesis SOP	72 of 2023
Balance of Probabilities SOP	73 of 2023

Changes from previous Instruments

ICD Coding

ICD-10-AM Codes: G58.7, G62, G63, G90

Brief description

The term peripheral neuropathy can be used to describe any disorder of the peripheral nervous system, i.e. those nerves outside the brain and spinal cord. This can include polyneuropathy (a process affecting many peripheral nerves), radiculopathy (a damaged nerve root in the spinal canal causing problems along the course of the nerve) and mononeuropathy (focal involvement of a single nerve). Peripheral neuropathy can involve sensory, motor or autonomic nervous functioning. The SOP covers non-traumatic polyneuropathies and some other specific conditions, but not isolated mononeuropathies.

Confirming the diagnosis

This SOP covers some but not all of the disorders of the peripheral nerves. Before applying the SOP, check that the claimed condition is not one of the many neuropathies excluded from this SOP (see list, below). Generally for the SOP to apply, the disorder will involve multiple peripheral nerves. Consistent symptoms need to be present. Signs of peripheral neuropathy and/or positive electromyography (nerve conduction) test results are also required to apply this SOP.

The appropriate medical specialist is a neurologist.

Additional diagnoses covered by SOP

Peripheral autonomic neuropathy
Mononeuritis multiplex
Polyneuropathy

Additional diagnoses that may be covered by SOP

Plexopathy (excluding thoracic outlet syndrome or other nerve compression or trauma-related disorders)
Radiculopathy that is non-traumatic:
- entrapment or compression of nerve roots by spondylosis, intervertebral disc prolapse, spinal stenosisis or other pathologies involving trauma to the nerve roots is excluded
- immune polyradiculopathy is excluded

Conditions not covered by SOP

Amyotrophic lateral sclerosis* - motor neuron disease SOP
Autoimmune nodopathy^#
Bell’s palsy^#
Carpal tunnel syndrome*
Cerebrovascular accident*
Cerebral tumors *
Charcot-Marie-Tooth disease*
Chronic immune polyradiculopathy (sensory and/or motor)^#
Chronic inflammatory demyelimating polyneuropathy^#
Complex regional pain syndrome*
Congenital/hereditary neuropathies^#
Cranial nerve disorders/neuropathies
Cubital tunnel synmdrome^#
Guillian-Barré syndrome*
Intercostal neuropathies^#
Meralgia paraesthetica^#
Mononeuropathies - may be covered by separate SOPs e.g. carpal tunnel syndrome
Morton metatarsalgia/neuralgia/neuroma*
Motor neuron disease*
Multifocal motor neuropathy^#
Multiple sclerosis*
Muscle disorders^#
Myasthenia gravis*
Myelitis^#
Myelopathy^#
Myopathies^#
Neuralgic amyotrophy^#
Neurogenic thoracic outlet syndrome* - thoracic outlet syndrome SOP
Neuromuscular disorders^#
Neuropathies due to trauma (burn, electrical injury, traumatic brain injuries)
Periodic limb movement disorder*
Restless legs syndrome*
Sciatica - may be covered by thoracolumbar spondylosis or intervertebral disc prolapse SOPs
Tarsal tunnel syndrome^#
Trigeminal neuralgia*
Trigeminal neuropathy*
Ulnar neuropathy at the elbow*

* another SOP applies

^#non-SOP condition

Clinical onset

The nature of the clinical onset depends on the type or neuropathy and the cause of the condition. Onset may be sudden or gradual. A common presentation is a distal, symmetric sensory loss, burning, or weakness in the lower limbs.

Clinical worsening

Appropriate clinical management varies but may involve treatment of any underlying disease, cessation of exposure to any triggering substance and alleviation of symptoms. Consideration of whether there has been worsening beyond the normal course of the condition will generally require specialist medical opinion.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/n-p/peripheral-neuropathy-f058-337033793545357/rulebase-peripheral-neuropathy/treatment-cisplatin

Peripheral Neuropathy F058

Current RMA Instruments

Changes from previous Instruments

ICD Coding

Brief description

Confirming the diagnosis

Additional diagnoses covered by SOP

Additional diagnoses that may be covered by SOP

Conditions not covered by SOP

Clinical onset

Clinical worsening

Rulebase for peripheral neuropathy

A haematological or lymphoproliferative disorder

Current RMA Instruments

Changes from previous Instruments

ICD Coding

Brief description

Confirming the diagnosis

Additional diagnoses covered by SOP

Additional diagnoses that may be covered by SOP

Conditions not covered by SOP

Clinical onset

Clinical worsening

A nutritional deficiency

Current RMA Instruments

Changes from previous Instruments

ICD Coding

Brief description

Confirming the diagnosis

Additional diagnoses covered by SOP

Additional diagnoses that may be covered by SOP

Conditions not covered by SOP

Clinical onset

Clinical worsening

A systemic disease for peripheral neuropathy

Current RMA Instruments

Changes from previous Instruments

ICD Coding

Brief description

Confirming the diagnosis

Additional diagnoses covered by SOP

Additional diagnoses that may be covered by SOP

Conditions not covered by SOP

Clinical onset

Clinical worsening

A systemic vasculitis

Current RMA Instruments

Changes from previous Instruments

ICD Coding

Brief description

Confirming the diagnosis

Additional diagnoses covered by SOP

Additional diagnoses that may be covered by SOP

Conditions not covered by SOP

Clinical onset

Clinical worsening

A viral or bacterial or protozoal infection

Current RMA Instruments

Changes from previous Instruments

ICD Coding

Brief description

Confirming the diagnosis

Additional diagnoses covered by SOP

Additional diagnoses that may be covered by SOP

Conditions not covered by SOP

Clinical onset

Clinical worsening

Acute cholinergic poisoning

Current RMA Instruments

Changes from previous Instruments

ICD Coding

Brief description

Confirming the diagnosis

Additional diagnoses covered by SOP

Additional diagnoses that may be covered by SOP

Conditions not covered by SOP

Clinical onset

Clinical worsening

Alcohol consumption

Current RMA Instruments