Chronic Myeloid Leukaemia B016
Current RMA Instruments
| Reasonable Hypothesis SOP | 57 of 2023 |
| Balance of Probabilities SOP | 58 of 2023 |
Changes from previous Instruments
ICD Coding
ICD-10-AM Code C92.1
Brief description
This is a malignant neoplasm of white blood cells, involving increased and unregulated production of the myeloid line of cells (predominantly neutrophils, but also basophils and eosinophils) in the bone marrow. It is associated with specific gene abnormalities.
Confirming the diagnosis
Confirmation of the diagnosis is typically based on findings from bone marrow aspiration and biopsy together with genetic testing.
The relevant medical specialists are a haematologist and a pathologist.
Additional diagnoses covered by SOP
- Chronic myelogenous leukaemia
- Chronic granulocytic leukaemia
- Chronic myeloblastic leukaemia
- Chronic myelocytic leukaemia
Conditions excluded from SOP
- Acute myeloid leukaemia*
- Atypical chronic myeloid leukaemia#
- Chronic eosinophilic leukaemia#
- Chronic neutrophilic leukaemia#
- Leukemoid reactions#
- Chronic lymphocytic leukaemia* - mature B-cell lymphoid leukaemia and small lymphocytic lymphoma SOP
- Chronic lymphoid leukaemia*
- Chronic myelomonocytic leukaemia#
- Myelodysplastic disorder*
* another SOP applies
# non-SOP condition
Clinical onset
The condition may be asymptomatic and first suspected following a blood test. Symptomatic presentations may include fatigue, weight loss, bleeding episodes, excessive sweating and abdominal fullness. An enlarged spleen may be found on examination. Average age of onset is around 60 years old.
Clinical worsening
The only SOP worsening factor is for inability to obtain appropriate clinical management. The condition is potentially curable with a hematopoietic cell transplant. The condition can now also be controlled long term (without cure) using tyrosine kinase inhibitors.
Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/chronic-myeloid-leukaemia-b016-c921
Rulebase for chronic myeloid leukaemia
<h5>Current RMA Instruments</h5><table border="1" cellpadding="1" cellspacing="1"><tbody><tr><td><address><a href="http://www.rma.gov.au/assets/SOP/2023/d9a58b8543/057.pdf" target="_blank">Reasonable Hypothesis SOP</a></address></td><td><span>57 of 2023</span></td></tr><tr><td><a href="http://www.rma.gov.au/assets/SOP/2023/8f1604302e/058.pdf" target="_blank">Balance of Probabilities SOP</a></td><td><span>58 of 2023</span></td></tr></tbody></table><h5>Changes from previous Instruments</h5><p><drupal-media data-entity-type="media" data-entity-uuid="e0486ee2-62b5-4a48-87f8-e9f80b9d0566" data-view-mode="wysiwyg"></drupal-media></p><h5>ICD Coding</h5><p>ICD-10-AM Code C92.1</p><h5>Brief description</h5><p>This is a malignant neoplasm of white blood cells, involving increased and unregulated production of the myeloid line of cells (predominantly neutrophils, but also basophils and eosinophils) in the bone marrow. It is associated with specific gene abnormalities.</p><h5><strong>Confirming the diagnosis</strong><strong> </strong></h5><p>Confirmation of the diagnosis is typically based on findings from bone marrow aspiration and biopsy together with genetic testing. </p><p>The relevant medical specialists are a haematologist and a pathologist.</p><h5><strong>Additional diagnoses covered by SOP</strong></h5><ul><li>Chronic myelogenous leukaemia</li><li>Chronic granulocytic leukaemia</li><li>Chronic myeloblastic leukaemia</li><li>Chronic myelocytic leukaemia</li></ul><h5><strong>Conditions excluded from SOP </strong></h5><ul><li>Acute myeloid leukaemia*</li><li>Atypical chronic myeloid leukaemia<sup><span>#</span></sup></li><li>Chronic eosinophilic leukaemia<sup><span>#</span></sup></li><li>Chronic neutrophilic leukaemia<sup><span>#</span></sup></li><li>Leukemoid reactions<sup><span>#</span></sup></li><li>Chronic lymphocytic leukaemia* - mature B-cell lymphoid leukaemia and small lymphocytic lymphoma SOP</li><li>Chronic lymphoid leukaemia*</li><li>Chronic myelomonocytic leukaemia<sup><span>#</span></sup> </li><li>Myelodysplastic disorder*</li></ul><p>* another SOP applies</p><p><sup><span># </span></sup>non-SOP condition</p><h5><strong>Clinical onset</strong></h5><p>The condition may be asymptomatic and first suspected following a blood test. Symptomatic presentations may include fatigue, weight loss, bleeding episodes, excessive sweating and abdominal fullness. An enlarged spleen may be found on examination. Average age of onset is around 60 years old.</p><h5>Clinical worsening</h5><p>The only SOP worsening factor is for inability to obtain appropriate clinical management. The condition is potentially curable with a hematopoietic cell transplant. The condition can now also be controlled long term (without cure) using tyrosine kinase inhibitors.</p><p> </p>
Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/chronic-myeloid-leukaemia-b016-c921/rulebase-chronic-myeloid-leukaemia
Atomic radiation
Current RMA Instruments
| Reasonable Hypothesis SOP | 57 of 2023 |
| Balance of Probabilities SOP | 58 of 2023 |
Changes from previous Instruments
ICD Coding
ICD-10-AM Code C92.1
Brief description
This is a malignant neoplasm of white blood cells, involving increased and unregulated production of the myeloid line of cells (predominantly neutrophils, but also basophils and eosinophils) in the bone marrow. It is associated with specific gene abnormalities.
Confirming the diagnosis
Confirmation of the diagnosis is typically based on findings from bone marrow aspiration and biopsy together with genetic testing.
The relevant medical specialists are a haematologist and a pathologist.
Additional diagnoses covered by SOP
- Chronic myelogenous leukaemia
- Chronic granulocytic leukaemia
- Chronic myeloblastic leukaemia
- Chronic myelocytic leukaemia
Conditions excluded from SOP
- Acute myeloid leukaemia*
- Atypical chronic myeloid leukaemia#
- Chronic eosinophilic leukaemia#
- Chronic neutrophilic leukaemia#
- Leukemoid reactions#
- Chronic lymphocytic leukaemia* - mature B-cell lymphoid leukaemia and small lymphocytic lymphoma SOP
- Chronic lymphoid leukaemia*
- Chronic myelomonocytic leukaemia#
- Myelodysplastic disorder*
* another SOP applies
# non-SOP condition
Clinical onset
The condition may be asymptomatic and first suspected following a blood test. Symptomatic presentations may include fatigue, weight loss, bleeding episodes, excessive sweating and abdominal fullness. An enlarged spleen may be found on examination. Average age of onset is around 60 years old.
Clinical worsening
The only SOP worsening factor is for inability to obtain appropriate clinical management. The condition is potentially curable with a hematopoietic cell transplant. The condition can now also be controlled long term (without cure) using tyrosine kinase inhibitors.
Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/chronic-myeloid-leukaemia-b016-c921/rulebase-chronic-myeloid-leukaemia/atomic-radiation
Cigar smoking
Current RMA Instruments
| Reasonable Hypothesis SOP | 57 of 2023 |
| Balance of Probabilities SOP | 58 of 2023 |
Changes from previous Instruments
ICD Coding
ICD-10-AM Code C92.1
Brief description
This is a malignant neoplasm of white blood cells, involving increased and unregulated production of the myeloid line of cells (predominantly neutrophils, but also basophils and eosinophils) in the bone marrow. It is associated with specific gene abnormalities.
Confirming the diagnosis
Confirmation of the diagnosis is typically based on findings from bone marrow aspiration and biopsy together with genetic testing.
The relevant medical specialists are a haematologist and a pathologist.
Additional diagnoses covered by SOP
- Chronic myelogenous leukaemia
- Chronic granulocytic leukaemia
- Chronic myeloblastic leukaemia
- Chronic myelocytic leukaemia
Conditions excluded from SOP
- Acute myeloid leukaemia*
- Atypical chronic myeloid leukaemia#
- Chronic eosinophilic leukaemia#
- Chronic neutrophilic leukaemia#
- Leukemoid reactions#
- Chronic lymphocytic leukaemia* - mature B-cell lymphoid leukaemia and small lymphocytic lymphoma SOP
- Chronic lymphoid leukaemia*
- Chronic myelomonocytic leukaemia#
- Myelodysplastic disorder*
* another SOP applies
# non-SOP condition
Clinical onset
The condition may be asymptomatic and first suspected following a blood test. Symptomatic presentations may include fatigue, weight loss, bleeding episodes, excessive sweating and abdominal fullness. An enlarged spleen may be found on examination. Average age of onset is around 60 years old.
Clinical worsening
The only SOP worsening factor is for inability to obtain appropriate clinical management. The condition is potentially curable with a hematopoietic cell transplant. The condition can now also be controlled long term (without cure) using tyrosine kinase inhibitors.
Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/chronic-myeloid-leukaemia-b016-c921/rulebase-chronic-myeloid-leukaemia/cigar-smoking
Cigarette smoking
Current RMA Instruments
| Reasonable Hypothesis SOP | 57 of 2023 |
| Balance of Probabilities SOP | 58 of 2023 |
Changes from previous Instruments
ICD Coding
ICD-10-AM Code C92.1
Brief description
This is a malignant neoplasm of white blood cells, involving increased and unregulated production of the myeloid line of cells (predominantly neutrophils, but also basophils and eosinophils) in the bone marrow. It is associated with specific gene abnormalities.
Confirming the diagnosis
Confirmation of the diagnosis is typically based on findings from bone marrow aspiration and biopsy together with genetic testing.
The relevant medical specialists are a haematologist and a pathologist.
Additional diagnoses covered by SOP
- Chronic myelogenous leukaemia
- Chronic granulocytic leukaemia
- Chronic myeloblastic leukaemia
- Chronic myelocytic leukaemia
Conditions excluded from SOP
- Acute myeloid leukaemia*
- Atypical chronic myeloid leukaemia#
- Chronic eosinophilic leukaemia#
- Chronic neutrophilic leukaemia#
- Leukemoid reactions#
- Chronic lymphocytic leukaemia* - mature B-cell lymphoid leukaemia and small lymphocytic lymphoma SOP
- Chronic lymphoid leukaemia*
- Chronic myelomonocytic leukaemia#
- Myelodysplastic disorder*
* another SOP applies
# non-SOP condition
Clinical onset
The condition may be asymptomatic and first suspected following a blood test. Symptomatic presentations may include fatigue, weight loss, bleeding episodes, excessive sweating and abdominal fullness. An enlarged spleen may be found on examination. Average age of onset is around 60 years old.
Clinical worsening
The only SOP worsening factor is for inability to obtain appropriate clinical management. The condition is potentially curable with a hematopoietic cell transplant. The condition can now also be controlled long term (without cure) using tyrosine kinase inhibitors.
Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/chronic-myeloid-leukaemia-b016-c921/rulebase-chronic-myeloid-leukaemia/cigarette-smoking
No appropriate clinical management for chronic myeloid leukaemia
Current RMA Instruments
| Reasonable Hypothesis SOP | 57 of 2023 |
| Balance of Probabilities SOP | 58 of 2023 |
Changes from previous Instruments
ICD Coding
ICD-10-AM Code C92.1
Brief description
This is a malignant neoplasm of white blood cells, involving increased and unregulated production of the myeloid line of cells (predominantly neutrophils, but also basophils and eosinophils) in the bone marrow. It is associated with specific gene abnormalities.
Confirming the diagnosis
Confirmation of the diagnosis is typically based on findings from bone marrow aspiration and biopsy together with genetic testing.
The relevant medical specialists are a haematologist and a pathologist.
Additional diagnoses covered by SOP
- Chronic myelogenous leukaemia
- Chronic granulocytic leukaemia
- Chronic myeloblastic leukaemia
- Chronic myelocytic leukaemia
Conditions excluded from SOP
- Acute myeloid leukaemia*
- Atypical chronic myeloid leukaemia#
- Chronic eosinophilic leukaemia#
- Chronic neutrophilic leukaemia#
- Leukemoid reactions#
- Chronic lymphocytic leukaemia* - mature B-cell lymphoid leukaemia and small lymphocytic lymphoma SOP
- Chronic lymphoid leukaemia*
- Chronic myelomonocytic leukaemia#
- Myelodysplastic disorder*
* another SOP applies
# non-SOP condition
Clinical onset
The condition may be asymptomatic and first suspected following a blood test. Symptomatic presentations may include fatigue, weight loss, bleeding episodes, excessive sweating and abdominal fullness. An enlarged spleen may be found on examination. Average age of onset is around 60 years old.
Clinical worsening
The only SOP worsening factor is for inability to obtain appropriate clinical management. The condition is potentially curable with a hematopoietic cell transplant. The condition can now also be controlled long term (without cure) using tyrosine kinase inhibitors.
Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/chronic-myeloid-leukaemia-b016-c921/rulebase-chronic-myeloid-leukaemia/no-appropriate-clinical-management-chronic-myeloid-leukaemia
Pipe smoking
Current RMA Instruments
| Reasonable Hypothesis SOP | 57 of 2023 |
| Balance of Probabilities SOP | 58 of 2023 |
Changes from previous Instruments
ICD Coding
ICD-10-AM Code C92.1
Brief description
This is a malignant neoplasm of white blood cells, involving increased and unregulated production of the myeloid line of cells (predominantly neutrophils, but also basophils and eosinophils) in the bone marrow. It is associated with specific gene abnormalities.
Confirming the diagnosis
Confirmation of the diagnosis is typically based on findings from bone marrow aspiration and biopsy together with genetic testing.
The relevant medical specialists are a haematologist and a pathologist.
Additional diagnoses covered by SOP
- Chronic myelogenous leukaemia
- Chronic granulocytic leukaemia
- Chronic myeloblastic leukaemia
- Chronic myelocytic leukaemia
Conditions excluded from SOP
- Acute myeloid leukaemia*
- Atypical chronic myeloid leukaemia#
- Chronic eosinophilic leukaemia#
- Chronic neutrophilic leukaemia#
- Leukemoid reactions#
- Chronic lymphocytic leukaemia* - mature B-cell lymphoid leukaemia and small lymphocytic lymphoma SOP
- Chronic lymphoid leukaemia*
- Chronic myelomonocytic leukaemia#
- Myelodysplastic disorder*
* another SOP applies
# non-SOP condition
Clinical onset
The condition may be asymptomatic and first suspected following a blood test. Symptomatic presentations may include fatigue, weight loss, bleeding episodes, excessive sweating and abdominal fullness. An enlarged spleen may be found on examination. Average age of onset is around 60 years old.
Clinical worsening
The only SOP worsening factor is for inability to obtain appropriate clinical management. The condition is potentially curable with a hematopoietic cell transplant. The condition can now also be controlled long term (without cure) using tyrosine kinase inhibitors.
Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/chronic-myeloid-leukaemia-b016-c921/rulebase-chronic-myeloid-leukaemia/pipe-smoking
Smoking tobacco products - material contribution
Current RMA Instruments
| Reasonable Hypothesis SOP | 57 of 2023 |
| Balance of Probabilities SOP | 58 of 2023 |
Changes from previous Instruments
ICD Coding
ICD-10-AM Code C92.1
Brief description
This is a malignant neoplasm of white blood cells, involving increased and unregulated production of the myeloid line of cells (predominantly neutrophils, but also basophils and eosinophils) in the bone marrow. It is associated with specific gene abnormalities.
Confirming the diagnosis
Confirmation of the diagnosis is typically based on findings from bone marrow aspiration and biopsy together with genetic testing.
The relevant medical specialists are a haematologist and a pathologist.
Additional diagnoses covered by SOP
- Chronic myelogenous leukaemia
- Chronic granulocytic leukaemia
- Chronic myeloblastic leukaemia
- Chronic myelocytic leukaemia
Conditions excluded from SOP
- Acute myeloid leukaemia*
- Atypical chronic myeloid leukaemia#
- Chronic eosinophilic leukaemia#
- Chronic neutrophilic leukaemia#
- Leukemoid reactions#
- Chronic lymphocytic leukaemia* - mature B-cell lymphoid leukaemia and small lymphocytic lymphoma SOP
- Chronic lymphoid leukaemia*
- Chronic myelomonocytic leukaemia#
- Myelodysplastic disorder*
* another SOP applies
# non-SOP condition
Clinical onset
The condition may be asymptomatic and first suspected following a blood test. Symptomatic presentations may include fatigue, weight loss, bleeding episodes, excessive sweating and abdominal fullness. An enlarged spleen may be found on examination. Average age of onset is around 60 years old.
Clinical worsening
The only SOP worsening factor is for inability to obtain appropriate clinical management. The condition is potentially curable with a hematopoietic cell transplant. The condition can now also be controlled long term (without cure) using tyrosine kinase inhibitors.
Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/chronic-myeloid-leukaemia-b016-c921/rulebase-chronic-myeloid-leukaemia/smoking-tobacco-products-material-contribution
Undergoing a course of therapeutic radiation
Current RMA Instruments
| Reasonable Hypothesis SOP | 57 of 2023 |
| Balance of Probabilities SOP | 58 of 2023 |
Changes from previous Instruments
ICD Coding
ICD-10-AM Code C92.1
Brief description
This is a malignant neoplasm of white blood cells, involving increased and unregulated production of the myeloid line of cells (predominantly neutrophils, but also basophils and eosinophils) in the bone marrow. It is associated with specific gene abnormalities.
Confirming the diagnosis
Confirmation of the diagnosis is typically based on findings from bone marrow aspiration and biopsy together with genetic testing.
The relevant medical specialists are a haematologist and a pathologist.
Additional diagnoses covered by SOP
- Chronic myelogenous leukaemia
- Chronic granulocytic leukaemia
- Chronic myeloblastic leukaemia
- Chronic myelocytic leukaemia
Conditions excluded from SOP
- Acute myeloid leukaemia*
- Atypical chronic myeloid leukaemia#
- Chronic eosinophilic leukaemia#
- Chronic neutrophilic leukaemia#
- Leukemoid reactions#
- Chronic lymphocytic leukaemia* - mature B-cell lymphoid leukaemia and small lymphocytic lymphoma SOP
- Chronic lymphoid leukaemia*
- Chronic myelomonocytic leukaemia#
- Myelodysplastic disorder*
* another SOP applies
# non-SOP condition
Clinical onset
The condition may be asymptomatic and first suspected following a blood test. Symptomatic presentations may include fatigue, weight loss, bleeding episodes, excessive sweating and abdominal fullness. An enlarged spleen may be found on examination. Average age of onset is around 60 years old.
Clinical worsening
The only SOP worsening factor is for inability to obtain appropriate clinical management. The condition is potentially curable with a hematopoietic cell transplant. The condition can now also be controlled long term (without cure) using tyrosine kinase inhibitors.
Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/chronic-myeloid-leukaemia-b016-c921/rulebase-chronic-myeloid-leukaemia/undergoing-course-therapeutic-radiation