A specified type of hepatitis

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/specified-type-hepatitis

Alcohol consumption

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/alcohol-consumption

Alpha-1 antitrypsin deficiency

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/alpha-1-antitrypsin-deficiency

Atomic radiation to the liver

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/atomic-radiation-liver

Blockage to the passage of bile

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/blockage-passage-bile

Budd-Chiari syndrome

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/budd-chiari-syndrome

Exposure to carbon tetrachloride

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/exposure-carbon-tetrachloride

Gaucher's disease

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/gauchers-disease

HIV in the presence of chronic infection with hepatitis B or C virus

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/hiv-presence-chronic-infection-hepatitis-b-or-c-virus

Inability to obtain appropriate clinical management for cirrhosis of the liver

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/inability-obtain-appropriate-clinical-management-cirrhosis-liver

Inhaling gaseous vinyl chloride

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/inhaling-gaseous-vinyl-chloride

Ionising radiation to the liver

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/ionising-radiation-liver

Iron overload involving the liver

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/iron-overload-involving-liver

Methotrexate

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/methotrexate

Schistosomiasis involving the liver

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/schistosomiasis-involving-liver

Severe right-sided cardiac failure

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/severe-right-sided-cardiac-failure

Thorium dioxide (Thorotrast)

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/thorium-dioxide-thorotrast

Veno-occlusive disease

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/veno-occlusive-disease

Vitamin A consumption

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/vitamin-consumption

Wilson's disease

Current RMA Instruments

Reasonable Hypothesis SOP	1 of 2017
Balance of Probabilities SOP	2 of 2017

Changes from previous Instruments

ICD Coding

ICD-9-CM Codes: 571.2, 571.5, 571.6, 573.3
ICD-10-AM Codes: K70.3, K71.7, K74.3-K74.6

Brief description

Cirrhosis is a form of chronic liver disease in which normal liver tissue is replaced by scarring and nodules of regenerating liver cells. It is a final common pathway of many types of chronic liver injury.

Confirming the diagnosis

The diagnosis can be made based on the clinical, laboratory, and radiologic findings in combination. A liver biopsy is required for definitive diagnosis, but is generally not necessary if other findings strongly suggests the presence of cirrhosis.

The relevant medical specialist is a gastroenterologist or a hepatologist.

Diagnoses covered by SOP

Alcoholic cirrhosis
Biliary cirrhosis
Cryptogenic cirrhosis
Post-hepatitic cirrhosis

Conditions not covered by SOP

Steatohepatitis*

* another SOP applies

Clinical onset

Cirrhosis is late stage liver disease, so the first symptoms, signs or other evidence of liver disease will not represent the clinical onset of cirrhosis. Clinical onset for cirrhosis will correspond to when the diagnosis (of cirrhosis) was first confirmed.

Clinical worsening

The course of cirrhosis is variable. Patients can be stabilised with appropriate treatment. However, patients with cirrhosis are susceptible to a variety of complications, and their life expectancy is markedly reduced. Cirrhosis is generally considered to be irreversible in its advanced stages, at which point the only treatment option may be liver transplantation. Reversal of cirrhosis in its earlier stages has been documented in some cases following treatment of the underlying cause.

Source URL: https://clik.dva.gov.au/ccps-medical-research-library/statements-principles/c-d/cirrhosis-liver-j017-k703k717k743-k746/rulebase-cirrhosis-liver/wilsons-disease

Cirrhosis of the Liver J017

Current RMA Instruments

Changes from previous Instruments

ICD Coding

Brief description

Confirming the diagnosis

Diagnoses covered by SOP

Conditions not covered by SOP

Clinical onset

Clinical worsening

Rulebase for cirrhosis of the liver

A specified type of hepatitis

Current RMA Instruments

Changes from previous Instruments

ICD Coding

Brief description

Confirming the diagnosis

Diagnoses covered by SOP

Conditions not covered by SOP

Clinical onset

Clinical worsening

Alcohol consumption

Current RMA Instruments

Changes from previous Instruments

ICD Coding

Brief description

Confirming the diagnosis

Diagnoses covered by SOP

Conditions not covered by SOP

Clinical onset

Clinical worsening

Alpha-1 antitrypsin deficiency

Current RMA Instruments

Changes from previous Instruments

ICD Coding

Brief description

Confirming the diagnosis

Diagnoses covered by SOP

Conditions not covered by SOP

Clinical onset

Clinical worsening

Atomic radiation to the liver

Current RMA Instruments

Changes from previous Instruments

ICD Coding

Brief description

Confirming the diagnosis

Diagnoses covered by SOP

Conditions not covered by SOP

Clinical onset

Clinical worsening

Blockage to the passage of bile

Current RMA Instruments

Changes from previous Instruments

ICD Coding

Brief description

Confirming the diagnosis

Diagnoses covered by SOP

Conditions not covered by SOP

Clinical onset

Clinical worsening

Budd-Chiari syndrome

Current RMA Instruments

Changes from previous Instruments

ICD Coding

Brief description

Confirming the diagnosis

Diagnoses covered by SOP

Conditions not covered by SOP

Clinical onset

Clinical worsening

Exposure to carbon tetrachloride

Current RMA Instruments

Changes from previous Instruments

ICD Coding

Brief description

Confirming the diagnosis

Diagnoses covered by SOP

Conditions not covered by SOP

Clinical onset