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Chronic Fatigue Syndrome F024

Last amended 
3 June 2015
Current RMA Instruments:
Reasonable Hypothesis SOP
11 of 2014
Balance of Probabilities SOP
12 of 2014
Changes from Previous Instruments:

SOP Bulletin 171

ICD Coding:
  • ICD-9-CM Codes: 780.7,799.3
  • ICD-10-AM Codes: R53, G93.3

This is a set of unexplained symptoms which is characterised by the onset of chronic fatigue which cannot be improved by bed rest which is interfering with the person’s work and daily activities.

Is specific diagnostic evidence required to apply the SOP?Yes. 

Specific diagnostic criteria (as per the SOP definition) must be met.  This diagnosis should be accepted with caution and only after other chronic conditions, including pre-existing psychiatric diseases, have been satisfactorily excluded.  To confirm this diagnosis you will therefore need a detailed medical report indicating that other potential causes for the patient’s condition have been appropriately investigated and ruled out (see the list below for examples).  An assessment by a psychiatrist will allow psychiatric conditions to be excluded.

Are there sub-factors that require specific information? – No.
Related conditions that may be covered by SOP (further information required)
  • myalgic encephalomyelitis
  • post viral fatigue (syndrome)
Examples of conditions which if present preclude the diagnosis of chronic fatigue syndrome

(this list is not exhaustive, seek medical advice if in doubt)

  • alcohol or other substance use disorder
  • anaemia
  • bipolar disorder
  • chronic obstructive pulmonary disease; asthma.
  • delusional disorder
  • dementia of any type
  • eating disorders - anorexia nervosa or bulimia nervosa
  • hypothyroidism (inadequately treated)
  • ischaemic heart disease
  • major depressive disorder
  • schizophrenia
  • severe obesity (BMI ³ 45)
  • sleep apnoea (inadequately treated)
  • unresolved hepatitis B or C infection
Unconfirmed diagnosis

If, after applying the above information, you are unable to confirm the diagnosis, you should then seek medical officer advice about further investigation.