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Leptospirosis A054

Last amended 
29 June 2015
Current RMA Instruments:
Reasonable Hypothesis SOP
94 of 2014
Balance of Probabilities SOP
95 of 2014
Changes from Previous Instruments:

SOP Bulletin 178

ICD Coding:
  • ICD-9-CM Codes: 100, 100.0, 100.8, 100.81, 100.89, 100.9
  • ICD-10-AM Codes: A27

This is a clinical infectious disease caused by the spirochaete bacterium Leptospira. Asymptomatic leptospiral infection is not covered by the SOP.  The clinical illness can be mild or severe. In the mild type the presentation is an acute influenza-like illness with fever, chills, conjunctival redness, severe headache, nausea, vomiting and muscle pains.  The severe systemic disease involves the liver, kidney and blood and is also known as Weil’s disease. Note that in a number of cases the disease becomes asymptomatic and then relapses after 1-3 days.

Is specific diagnostic evidence required to apply the SOP?No.

This diagnosis is made on the microbiological microscopy and culture of the organism; or seroconversion.  The relevant medical specialist is an infectious disease physician.

Are there sub-factors that require specific diagnostic information? – No.
Additional diagnoses covered by SOP
  • Weil’s disease / syndrome.

Conditions excluded from SOP
  • Asymptomatic leptospiral infection
Unconfirmed diagnosis

If, after applying the above information, you are unable to confirm the diagnosis, you should then seek medical officer advice about further investigation.