You are here

Hypopituitarism C033

Last amended 
29 June 2015
Current RMA Instruments:
Reasonable Hypothesis SOP
76 of 2009
Balance of Probabilities SOP
77 of 2009
Changes from Previous Instruments:

SOP Bulletin 164

ICD Coding:
  • ICD-9-CM Codes: 253.2-253.9
  • ICD-10-AM Codes: E23.0, E23.2, E23.3, E23.6, E23.7

This SOP covers pathology of the pituitary and also pathology of the hypothalamus where it causes a deficiency in pituitary hormone production.

The pituitary produces a range of hormones: growth hormone; thyroid stimulating hormone; adrenocorticotrophic hormone; follicle stimulating hormone; lutenising hormone; prolactin; antidiuretic hormone/vasopressin; and oxytocin.  Hypopituitarism can cause a deficiency in one or more or all pituitary hormones, with a wide range of possible clinical manifestations.

Is specific diagnostic evidence required to apply the SOP? – Yes.

Endocrinological specialist opinion together with the requisite abnormal blood hormone levels is required.

Are there sub-factors that require specific information? – No.
Additional diagnoses covered by SOP
  • Acute hypopituitarism
  • Chronic hypopituitarism
  • Drug induced hypopituitarism
  • Diabetes insipidus
  • Panhypopituitarism
  • Sheehan’s syndrome
Conditions excluded from SOP
  • Adrenal insufficiency (SOP), ICD-9 code 255.4
  • Cushing’s disease (SOP), ICD-9 code 255.0
  • Cushing’s syndrome (SOP), ICD-9 code 255.0
Unconfirmed diagnosis

If, after applying the above information, you are unable to confirm the diagnosis, you should then seek medical officer advice about further investigation.