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Cushing's Syndrome C009

Last amended 
29 June 2015
Current RMA Instruments:
Reasonable Hypothesis SOP
33 of 2009
Balance of Probabilities SOP
34 of 2009
Changes from Previous Instruments:

SOP Bulletin 134

ICD Coding:
  • ICD-9-CM Codes: 255.0
  • ICD-10-AM Codes: E24.0, E24.2, E24.3, E24.8, E24.9

Cushing’s syndrome results from high levels of cortisol over a sustained period. Typical features include central obesity, hypertension, weakness, hirsutism, purplish streaks on the skin and oedema.

Is specific diagnostic evidence required to apply the SOP?No, but see comments, below.
Are there sub-factors that require specific information? – No.
Additional diagnoses covered by SOP
  • Cushing’s disease
  • Hypercortisolism
Unconfirmed diagnosis

If, after applying the above information, you are unable to confirm the diagnosis, you should then:

  1. seek medical officer advice about further investigation, or;
  2. generate a diagnostic report, or;
  3. re-encode the condition, if appropriate.

The following investigations may be useful in establishing the diagnosis.

  • Report from treating doctor

Cushing’s syndrome is commonly caused by taking corticosteroid drugs. Stopping or reducing such drugs will generally see the condition resolve. It may thus be a temporary, or short term condition. A "N.I.F." or "resolved" diagnosis may be appropriate if Cushing’s syndrome is no longer present.