You are here

Adrenal Insufficiency C032

Last amended 
15 June 2015
Current RMA Instruments:
Reasonable Hypothesis SOP
74 of 2009
Balance of Probabilities SOP
75 of 2009
Changes from Previous Instruments:

SOP Bulletin 138

ICD Coding:
  • ICD-9-CM Codes: 017.6, 255.4, 255.5, 036.3
  • ICD-10-AM Codes: E27.1, E27.2, E27.3, E27.4, E89.6, A39.1, A18.7

The adrenal gland produces the glucocorticoid cortisol and the mineralocorticoid aldosterone. Deficiency of these hormones can cause a wide range of symptoms including weakness, skin pigmentation, weight loss and low blood pressure. This SOP does not cover disease or injury of the adrenal medulla, which is involved in the secretion of adrenaline and noradrenaline.

Is specific diagnostic evidence required to apply the SOP? – Yes.

The diagnosis requires specialist opinion by an endocrinologist or general physician, after blood testing to measure specific hormone production has been carried out.

Are there sub-factors that require specific information? – No.
Additional diagnoses covered by SOP
  • Acute hypoadrenalism
  • Addison’s disease
  • Addisonian crisis
  • Adrenal crisis/Adrenocortical crisis
  • Chronic hypoadrenalism
  • Drug induced hypoadrenalism
  • Primary adrenocortical insufficiency
  • Secondary adrenocortical insufficiency
Conditions excluded from SOP
  • Adrenal medullary insufficiency, ICD-9 code 255.6
  • Cushing’s disease (SOP), ICD-9 code 255.0
  • Cushing’s syndrome (SOP), ICD-9 code 255.0
  • Hereditary forms of adrenal insufficiency
  • Hypopituitarism (SOP), ICD-9 code 253.2, 253.7
Unconfirmed diagnosis

If, after applying the above information, you are unable to confirm the diagnosis, you should then seek medical officer advice about further investigation.