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Treatment with pentamidine

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Last amended 
1 June 2015

Diabetes mellitus - Treatment with pentamidine Factor

Pentamidine injections (Pentacarinat) are used in the treatment of rare infections such as pneumocystis carinii pneumonia (PCP) - particularly due to AIDS, and leishmaniasis. Pentamidine can permanently destroy beta cells of the pancreas. For PCP the usual dose is once daily by IV injection for 14 days. For leishmaniasis the usual dose is 3 times a week to a maximum of 10 injections.

Last reviewed for CCPS 12 March 2008.

Preliminary questions [10540]

28237 there is some evidence that treatment with pentamidine may be a factor in the development or worsening of the condition under consideration.

10979 the veteran has been treated with pentamidine at some time.

10747 the veteran was treated with pentamidine for an illness or injury which is identifiable.

10748  the veteran has established the causal connection between the treatment with pentamidine and VEA service for diabetes mellitus.

28238 the veteran was treated with pentamidine for the identified illness or injury within the two years immediately before the clinical onset of the condition under consideration.

10749   the veteran has established the causal connection between the treatment with pentamidine and VEA service for the clinical onset of diabetes mellitus.

10753  the veteran has established the causal connection between the treatment with pentamidine and operational service for the clinical onset of diabetes mellitus.

or

10754  the veteran has established the causal connection between the treatment with pentamidine and eligible service for the clinical onset of diabetes mellitus.

or

7334     the clinical onset of the condition under consideration occurred after the end of the veteran's last period of VEA service.

7335     the condition under consideration permanently worsened.

28239 the veteran was treated with pentamidine for the identified illness or injury within the two years immediately before the clinical worsening of the condition under consideration.

10750   the veteran has established the causal connection between the treatment with pentamidine and VEA service for the clinical worsening of diabetes mellitus.

10755  the veteran has established the causal connection between the treatment with pentamidine and operational service for the clinical worsening of diabetes mellitus.

or

10756  the veteran has established the causal connection between the treatment with pentamidine and eligible service for the clinical worsening of diabetes mellitus.

Clinical onset and operational service [10753]

28240  the identified illness or injury for which the treatment with pentamidine was given is causally related to operational service.

Clinical onset and eligible service [10754]

28241  the identified illness or injury for which the treatment with pentamidine was given is causally related to eligible service.

Clinical worsening and operational service [10755]

28240  the identified illness or injury for which the treatment with pentamidine was given is causally related to operational service.

10763 the clinical onset of the condition under consideration occurred prior to that part of operational service to which the identified illness or injury for which the treatment with pentamidine was given is causally related.

Clinical worsening and eligible service [10756]

28241  the identified illness or injury for which the treatment with pentamidine was given is causally related to eligible service.

10764 the clinical onset of the condition under consideration occurred prior to that part of eligible service to which the identified illness or injury for which the treatment with pentamidine was given is causally related.